Borges, R. M., das Neves Costa, F., Chagas, F. O., Teixeira, A. M., Yoon, J., Weiss, M. B., Crnkovic, C. M., Pilon, A. C., Garrido, B. C., Betancur, L. A., Forero, A. M., Castellanos, L., Ramos, F. A., Pupo, M. T., Kuhn, S. Data Fusion‐based Discovery (DAFdiscovery) pipeline to aid compound annotation and bioactive compound discovery across diverse spectral data. Phytochemical Analysis (2022)

Berlinck, R.G.S., Crnkovic, C.M., Gubiani, J.R., Bernardi, D.I., Ióca, L.P., Quintana-Bulla, J.I. The isolation of water-soluble natural products – challenges, strategies and perspectives. Natural Product Reports (2022) 39:596-669

Tonon, L.A.C, Rua, C., Crnkovic, C.M., Bernardi, D.I., Pires Junior, O.R., Haddad, C.F.B., Pedrosa, C.S.G., Souza, L.R.Q., Rehen, S.K., Azevedo, G.P.R., Thompson, C.C. Thompson, F.L., Berlinck, R.G.S. Microbiome associated with the tetrodotoxin-bearing anuran Brachycephalus pitanga. Toxicon (2021) 203:139-146

Crnkovic, C.M., Caricati, C.P., Oliveira, R.P.S., Stephano, M.A. Biosafety applied in pharmaceutical and biotechnological processes. In: Pharmaceutical Biotechnology; Pessoa Jr, A., Vitolo, M., Long, P.F., Eds.; CRC Press/Taylor & Francis Group: Boca Raton, 2021; pp 313-324

Ióca, L.P., Dai, Y., Kunakom, S., Santos Júnior, P.L.T, Diaz-Espinosa, J., Krunic, A., Crnkovic, C.M., Orjala, J., Sanchez, L.M., Ferreira, A. G., Berlinck, R.G.S., Eustáquio, A.S. A novel family of nonribosomal peptides modulate collective behavior in Pseudovibrio bacteria isolated from marine sponges. Angewandte Chemie (2021) 60(29):15891-15898

Costa, J.H., Bazioli, J.M., Barbosa, L.D., Santos Júnior, P.L.T, Reis F.C.G., Klimeck, T., Crnkovic, C.M., Berlinck, R.G.S., Sussulini, A., Rodrigues, M.L., Fill, T.P. Phytotoxic tryptoquialanines produced in vivo by Penicillium digitatum are exported in extracellular vesicles. MBio (2021) 2(1): e03393-20

Jacinavicius, F.R., Geraldes, V., Crnkovic, C.M., Delbaje, E., Fiori, M., Pinto, E. Effect of ultraviolet radiation on the metabolomic profiles of potentially toxic cyanobacteria. FEMS Microbiol Ecol (2021) 1:fiaa243

May, D.S., Crnkovic, C.M., Krunic, A., Wilson, T.A., Fuchs, J.R., Orjala, J. 15N stable isotope labeling and comparative metabolomics facilitates genome mining in cultured cyanobacteria. ACS Chem Biol (2020) 15(3):758-765

Crnkovic, C.M., Braesel, J., Krunic, A., Eustáquio, A.S., Orjala, J. Scytodecamide from the Cultured Scytonema sp. UIC 10036 Expands the Chemical and Genetic Diversity of Cyanobactins. ChemBioChem (2020). 21(6):845-852

Prior to Jan, 2020

Guo Y*, Crnkovic CM*, Won KJ, Yang X, Lee JR, Orjala J, Lee H, Jeong H. Commensal gut bacteria convert the immunosuppressant tacrolimus to less potent metabolites. Drug Metab Dispos (2019) 47(3):194-202

Crnkovic CM, Krunic A, May DS, Wilson, TA. Kao D, Burdette JE, Fuchs JR, Oberlies NH, Orjala J. Calothrixamides A and B from the cultured cyanobacterium Calothrix sp. UIC 10520. J Nat Prod (2018) 81(9):2083-2090

Braesel J, Crnkovic CM, Kunstman K ,Green S, Maienschein-Cline M, Orjala J, Murphy BT, Eustaquio AS. Complete genome of Micromonospora sp. strain B006 reveals biosynthetic potential of a Lake Michigan actinomycete. J Nat Prod (2018) 81(9):2057-2068

Crnkovic CM, May DS & Orjala J. The impact of culture conditions on growth and metabolomic profiles of freshwater cyanobacteria. J Appl Phycol (2018) 30(1):375-384

Science communication

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Combinando tecnologia e biodiversidade para a descoberta de fármacos

EDEVO Darwin USP, Conversatório

Prospecção biotecnológica de produtos naturais a partir de cianobactérias

Webnários da Divisão de Produtos Naturais - SBQ

Pós-Graduação FCF-USP | Doutoranda Rhuana Valdetário Médice